Estudio descriptivo sobre la asociación entre el colesterol remanente y el riesgo de accidente cerebrovascular isquémico.
Fecha
2024-09-10
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Jaén: Universidad de Jaén
Resumen
[ES] La enfermedad cerebrovascular es una manifestación de la enfermedad cardiovascular, la principal causa
de muerte mundial, impulsada por factores de riesgo como dislipemia, diabetes mellitus e hipertensión
arterial. Se han identificado factores de riesgo cardiovascular "residual o persistente" como las
lipoproteínas ricas en triglicéridos, remanentes de colesterol, lipoproteína A e inflamación mediada por la
proteína C reactiva. El objetivo del estudio es analizar la asociación entre los remanentes de colesterol y
los eventos cerebrovasculares, mortalidad y tasa de reingreso. Se realizó un estudio descriptivo y
retrospectivo con 391 pacientes hospitalizados por ACV isquémico en 2022. Se calcularon los niveles de
remanentes de colesterol y se analizaron variables epidemiológicas, clínicas, diagnósticas y terapéuticas.
Se encontraron diferencias significativas en el tipo de ACV isquémico según los niveles de remanentes de
colesterol, con una mayor prevalencia de ACV aterotrombótico y diabetes mellitus tipo 2 en el cuartil
superior de remanentes de colesterol. No se encontraron asociaciones significativas con la mortalidad y
los reingresos
[EN] Cerebrovascular disease is a manifestation of cardiovascular disease, the leading cause of death worldwide, driven by risk factors such as dyslipidemia, diabetes mellitus, and arterial hypertension. “Residual or persistent” cardiovascular risk factors have been identified as triglyceride-rich lipoproteins, cholesterol remnants, lipoprotein A, and C-reactive protein-mediated inflammation. The aim of the study is to analyze the association between cholesterol remnants and cerebrovascular events, mortality and readmission rate. A descriptive and retrospective study was performed with 391 patients hospitalized for ischemic stroke in 2022. Cholesterol remnant levels were calculated and epidemiological, clinical, diagnostic and therapeutic variables were analyzed. Significant differences were found in the type of ischemic stroke according to cholesterol remnant levels, with a higher prevalence of atherothrombotic stroke and type 2 diabetes mellitus in the upper quartile of cholesterol remnants. No significant associations were found with mortality and readmissions.
[EN] Cerebrovascular disease is a manifestation of cardiovascular disease, the leading cause of death worldwide, driven by risk factors such as dyslipidemia, diabetes mellitus, and arterial hypertension. “Residual or persistent” cardiovascular risk factors have been identified as triglyceride-rich lipoproteins, cholesterol remnants, lipoprotein A, and C-reactive protein-mediated inflammation. The aim of the study is to analyze the association between cholesterol remnants and cerebrovascular events, mortality and readmission rate. A descriptive and retrospective study was performed with 391 patients hospitalized for ischemic stroke in 2022. Cholesterol remnant levels were calculated and epidemiological, clinical, diagnostic and therapeutic variables were analyzed. Significant differences were found in the type of ischemic stroke according to cholesterol remnant levels, with a higher prevalence of atherothrombotic stroke and type 2 diabetes mellitus in the upper quartile of cholesterol remnants. No significant associations were found with mortality and readmissions.