"ORGANIZACIÓN Y ESTRUCTURA DEL CROMOSOMA EUCARIOTA DURANTE MITOSIS".
Fecha
2020-10-19
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Jaén: Universidad de Jaén
Resumen
El estudio del cromosoma mitótico ha sido un constante a lo largo de los años. La falta de medios y controversias que aparecían en diferentes investigaciones han impedido aclarar los niveles de plegamiento cromosómicos durante la mitosis. En este trabajo se revisa, desde una perspectiva histórica, cómo ha ido progresando el entendimiento del cromosoma en organismos eucariotas desde los estudios clásicos hasta la actualidad, tras el desarrollo de la tecnología y el uso de técnicas nuevas que han tenido un impacto directo sobre la comprensión de la condensación cromosómica. Además, también se lleva a cabo una comparativa entre organismos eucariotas para analizar el grado de conservación evolutiva de este proceso.
The research of the mitotic chromosome has been constant through the years. Due to the lack of means and controversies that arose after different studies it has been difficult to explain the higher-order levels of the chromosome folding during mitosis. In this project it is reviewed, from an historical perspective, how the chromosome understanding in eukaryotes has progressed since the classical studies to nowadays, after the technology outbreak and the use of the new methods that have had a direct impact on our knowledge in chromosomal condensation, wrapping up with a small comparative between eukaryotic organisms from a conservative evolutionary perspective.
The research of the mitotic chromosome has been constant through the years. Due to the lack of means and controversies that arose after different studies it has been difficult to explain the higher-order levels of the chromosome folding during mitosis. In this project it is reviewed, from an historical perspective, how the chromosome understanding in eukaryotes has progressed since the classical studies to nowadays, after the technology outbreak and the use of the new methods that have had a direct impact on our knowledge in chromosomal condensation, wrapping up with a small comparative between eukaryotic organisms from a conservative evolutionary perspective.