Tipos de dieta y comportamiento. Papel del eje cerebro-intestino
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2024-01-11
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Jaén: Universidad de Jaén
Resumen
El continuo exilio de población rural hacia grandes ciudades ha generado múltiples cambios en la civilización, uno de ellos, el cambio de dieta. Tras este acontecimiento, ha aumentado la ingesta de dietas ricas en ácidos grasos saturados y azúcares, lo cual ha provocado de manera directa un cambio en la microbiota intestinal.
Gracias al estudio del eje intestino-cerebro, se ha podido conocer cómo el comportamiento del mismo se ve influenciado por la dieta. De modo que, un aumento en la ingesta de dietas con alto contenido en azúcares y grasas saturadas puede perturbar la microbiota intestinal, la cual modifica la señalización del eje intestino-cerebro, pudiendo provocar trastornos en el sujeto, tales como, obesidad, diabetes tipo 2, Parkinson, Alzheimer, ansiedad, depresión, bipolaridad, pérdida de memoria y autismo, entre otros.
En esta memoria se procederá a estudiar minuciosamente cómo influye la dieta en los mecanismos de señalización bacteriana, y cómo una disbiosis intestinal puede provocar trastornos cognitivos y mentales.
The continuous exile of rural population towards large cities has generated multiple changes in civilization, one of them, the diet ́s change. After this event, the intake of diets rich in saturated fatty acids and sugars has increased, which has directly caused a change in the gut microbiota. Thanks to the study of the gut-brain axis, it has been known how its behavior is influenced by diet. So, an increase in the intake of diets high in sugars and saturated fats can disturb the gut microbiota, which modifies the intestine-brain axis signaling, and can cause disorders in the subject, such as obesity, type 2 diabetes, Parkinson's, Alzheimer's, anxiety, depression, bipolarity, memory loss and autism, among others. In this report we will proceed to study in detail how the diet influences the mechanisms of bacterial signaling, and how a gut dysbiosis can cause cognitive and mental disorders.
The continuous exile of rural population towards large cities has generated multiple changes in civilization, one of them, the diet ́s change. After this event, the intake of diets rich in saturated fatty acids and sugars has increased, which has directly caused a change in the gut microbiota. Thanks to the study of the gut-brain axis, it has been known how its behavior is influenced by diet. So, an increase in the intake of diets high in sugars and saturated fats can disturb the gut microbiota, which modifies the intestine-brain axis signaling, and can cause disorders in the subject, such as obesity, type 2 diabetes, Parkinson's, Alzheimer's, anxiety, depression, bipolarity, memory loss and autism, among others. In this report we will proceed to study in detail how the diet influences the mechanisms of bacterial signaling, and how a gut dysbiosis can cause cognitive and mental disorders.