Estudio de la composición fenólica de plantas mediante cromatografía líquida acoplada a espectrometría de masas
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2018-02-27
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Jaén: Universidad de Jaén
Resumen
[ES] En este trabajo se han estudiado e identificado por vez primera los compuestos fenólicos mayoritarios de la planta Quercus Coccifera, utilizando para ello la técnica Cromatografía de Líquidos de Alta Resolución acoplada a Espectrometría de Masas. Entre los polifenoles identificados cabe destacar la Quercetina, compuesto que actualmente tiene múltiples aplicaciones comerciales debido a su gran actividad antioxidante y a sus múltiples propiedades beneficiosas para la salud. Se han identificado también algunos taninos hidrolizables como Digaloil Glucosa, Trigaloil Glucosa y Glucogalina, metabolitos que desde antiguo se han aislado de plantas medicinales debido a sus actividades biológicas y farmacológicas, entre las que cabe citar efectos antisecretores y antiulcerogénicos.
La información obtenida acerca de la composición del extracto fenólico de la planta Quercus Coccifera puede ser de gran utilidad a fin de llevar a cabo posteriores estudios acerca de la posibilidad de su uso para aplicaciones medicinales o elaboración de fármacos.
[EN] In this work the main phenolic compounds of the Quercus Coccifera plant have been studied and identified for the first time, making use of High Performance Liquid Chromatography coupled to Mass Spectrometry. Among the identified polyphenols, Quercetin is a compound that currently has multiple commercial applications due to its high antioxidant activity and its many beneficia! properties for health. Sorne hydrolysable tannins such as Digaloyl Glucose, Trigaloyl Glucose and Glucogaline have also been identified, metabolites that have been isolated from medicinal plants since ancient times due to their biological and pharmacological activities, including anti-secretory and antiulcerogenic effects. The information obtained about the composition of the phenolic extract of the Quercus Coccifera plant can be very useful in order to carry out further studies about the possibility of its use for medicinal applications or drug manufacture.
[EN] In this work the main phenolic compounds of the Quercus Coccifera plant have been studied and identified for the first time, making use of High Performance Liquid Chromatography coupled to Mass Spectrometry. Among the identified polyphenols, Quercetin is a compound that currently has multiple commercial applications due to its high antioxidant activity and its many beneficia! properties for health. Sorne hydrolysable tannins such as Digaloyl Glucose, Trigaloyl Glucose and Glucogaline have also been identified, metabolites that have been isolated from medicinal plants since ancient times due to their biological and pharmacological activities, including anti-secretory and antiulcerogenic effects. The information obtained about the composition of the phenolic extract of the Quercus Coccifera plant can be very useful in order to carry out further studies about the possibility of its use for medicinal applications or drug manufacture.