Polimorfismos asociados al Alzheimer; enzima convertidora de angiotensina
Archivos
NO SE HA AUTORIZADO la consulta de los documentos asociados
Fecha
2014-07-11
Autores
Título de la revista
ISSN de la revista
Título del volumen
Editor
Jaén: Universidad de Jaén
Resumen
[ES]Según numerosas investigaciones anteriores, el polimorfismo ACE parece
estar asociado a la enfermedad de Alzheimer, aunque en otros casos los
resultados han señalado que no existe relación entre el polimorfismo y la
posibilidad de padecer la enfermedad. En este estudio vamos a comparar las
frecuencias del polimorfismo entre personas sanas (estudiadas en este
proyecto) y personas enfermas (estudiadas en un proyecto anterior y cuyo
análisis se ha completado en este). El objetivo es averiguar si existen
diferencias significativas entre las frecuencias de este gen en ambos grupos de
individuos, para así poder demostrar si alguno de sus genotipos se asocia a un
aumento de la posibilidad de padecer Alzheimer.
[EN]According to many previous investigations, the ACE polymorphism seems to be associated with Alzheimer's disease (AD), but in other cases the results have indicated that there is no relation between the polymorphism and the possibility of developing the disease. In this study we compare the frequencies of polymorphism among healthy people (studied in this project) and sick people (discussed in an earlier work and completed in this project). Our objective is to determine if there are significant differences in the frequencies of this gene between both groups of people in order to know whether any of its genotypes can be associated to an increase in the probability of suffering from Alzheimer’s disease.
[EN]According to many previous investigations, the ACE polymorphism seems to be associated with Alzheimer's disease (AD), but in other cases the results have indicated that there is no relation between the polymorphism and the possibility of developing the disease. In this study we compare the frequencies of polymorphism among healthy people (studied in this project) and sick people (discussed in an earlier work and completed in this project). Our objective is to determine if there are significant differences in the frequencies of this gene between both groups of people in order to know whether any of its genotypes can be associated to an increase in the probability of suffering from Alzheimer’s disease.