Estudio ecológico-molecular de bacterias del ácido láctico intestinales en un modelo murino
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2016-02-22
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Jaén: Universidad de Jaén
Resumen
[ES] En los últimos años, el creciente interés por conocer de que se compone nuestra microbiota intestinal ha ido en aumento.
Se sabe que al nacer, los microorganismos que van a formar parte de nuestro sistema digestivo, son heredados de la propia comunidad bacteriana de la madre, y que ésta varía a lo largo de nuestra vida en función de muchos factores internos y externos.
En este estudio, nos vamos a centrar sólo en la composición de la microbiota natural adquirida desde el nacimiento y en el transcurso del tiempo, para comprobar si dicha microbiota, tiene un proceso natural de variabilidad que cambia con la edad, pero que se mantiene dentro de unos valores naturales.
Para ello hemos analizado las heces del intestino grueso de ocho ratones desde las 6 hasta las 18 semanas de vida. Además, las secuencias de las bacterias presentes en los mismos, han pasado a formar parte del Catálogo Metagenómico Universal.
[EN] In recent years, the interest in knowing the composition of our intestinal microbiota has increased. Numerous scientific research studies carried out in this area, including journal articles, scientific or popularization, promote the regular consumption of products now called functional foods or probiotics, praising its benefits for the body. It is known that at birth, the microorganisms that become part of our digestive system, are inherited from the bacterial community of the mother herself, and it varies throughout our lives depending on many internal and external factors. In this study, we will focus only on the study of the composition of natural microbiota acquired at birth and in the course of time, to verify if the microbiota composition is a natural process whose variability changes with age, but remains within of natural values. In order to achieve this, we have analyzed the feces from the large intestine of eight mice from 6 to 18 weeks. In addition, sequences of the bacterial present in them have become part of the Universal Catalog.
[EN] In recent years, the interest in knowing the composition of our intestinal microbiota has increased. Numerous scientific research studies carried out in this area, including journal articles, scientific or popularization, promote the regular consumption of products now called functional foods or probiotics, praising its benefits for the body. It is known that at birth, the microorganisms that become part of our digestive system, are inherited from the bacterial community of the mother herself, and it varies throughout our lives depending on many internal and external factors. In this study, we will focus only on the study of the composition of natural microbiota acquired at birth and in the course of time, to verify if the microbiota composition is a natural process whose variability changes with age, but remains within of natural values. In order to achieve this, we have analyzed the feces from the large intestine of eight mice from 6 to 18 weeks. In addition, sequences of the bacterial present in them have become part of the Universal Catalog.