Controversia en el estudio sobre resistencias cruzadas entre antibióticos y desinfectantes (biocidas)
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2024-09-05
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En la actualidad, hay una gran preocupación en torno al desarrollo de resistencias cruzadas entre biocidas y antibióticos debido al uso constante de biocidas que producen una cierta tolerancia y a su vez, resistencia antibiótica, generando bacterias multirresistentes. Con esta revisión se quiere profundizar sobre el desarrollo de resistencias cruzadas entre antibióticos y distintos desinfectantes o biocidas. Empleando las distintas bases de datos como Google Académico o PubMed se obtuvo información sobre los diversos tipos de biocidas y antibióticos, sus respectivos mecanismos de acción y la relación que se produce entre ellos. Los compuestos derivados del amonio cuaternario, el triclosán y la clorhexidina son los biocidas más estudiados debido a su uso continuado, y por tanto, poseen una gran probabilidad de generar una resistencia cruzada a los antibióticos. Sin embargo, se necesita una mayor investigación al respecto para poder determinar las posibles resistencias con otros biocidas poco estudiados.
Currently, there is great concern about the development of cross-resistance between biocides and antibiotics due to the constant use of biocides that produce a certain tolerance and in turn, antibiotic resistance, generating multi-resistant bacteria. This review aims to delve into the development of cross- resistance between antibiotics and different disinfectants or biocides. Using different databases such as Google Scholar or PubMed, information was obtained on the various types of biocides and antibiotics, their respective mechanisms of action and the relationship between them. Compounds derived from quaternary ammonium, triclosan and chlorhexidine are the most studied biocides due to their continued use, and therefore have a high probability of generating cross-resistance to antibiotics. However, more research is needed in order to determine possible resistances with other poorly studied biocides.
Currently, there is great concern about the development of cross-resistance between biocides and antibiotics due to the constant use of biocides that produce a certain tolerance and in turn, antibiotic resistance, generating multi-resistant bacteria. This review aims to delve into the development of cross- resistance between antibiotics and different disinfectants or biocides. Using different databases such as Google Scholar or PubMed, information was obtained on the various types of biocides and antibiotics, their respective mechanisms of action and the relationship between them. Compounds derived from quaternary ammonium, triclosan and chlorhexidine are the most studied biocides due to their continued use, and therefore have a high probability of generating cross-resistance to antibiotics. However, more research is needed in order to determine possible resistances with other poorly studied biocides.