Terapia con de células madre adultas para la regeneración de tejido condral dañado.
Fecha
2015-06-16
Autores
Título de la revista
ISSN de la revista
Título del volumen
Editor
Jaén: Universidad de Jaén
Resumen
[ES] En la actualidad, ciertas enfermedades de origen osteocondral como son la artritis reumatoide o la artrosis en ciertas articulaciones, son de gran importancia en la sociedad. El único vehículo para solucionar estos problemas es la cirugía. Existen otras estrategias para resolver estas patologías que pueden ser de interés, en concreto la posibilidad de diferenciar células madre mesenquimales a condrocitos viables que sirvan para repoblar las zonas de cartílago dañadas en estas articulaciones.
La finalidad de esta revisión sistemática fue analizar la evidencia científica disponible para determinar la eficacia de la diferenciación de las células madre mesenquimales hacia condrocitos en enfermedades degenerativas de cartílago. Para ello se utilizó la base de datos PUBMED y se incluyeron ensayos clínicos aleatorizados, de no más de 10 años de antigüedad, realizados en humanos y que estuvieran disponibles a texto completo. Se encontraron un total de 451 artículos, de los cuáles siguiendo los criterios de elegibilidad, 11 forman parte de esta revisión.
[EN] Resently, certain diseases are osteochondral origin such as rheumatoid arthritis or osteoarthritis in certain joints, are of great importance in society. The only vehicle to solve these problems is surgery. There are other strategies to resolve these pathologies that may be of interest, namely the possibility of differentation mesenchymal stem cells to viable chondrocytes serve to repopulate the damaged areas of cartilage in these joints. The purpose of this review was to examine the available scientific evidence to determine the effectiveness of the differentiation of mesenchymal stem cells into chondrocytes in cartilage degenerative diseases. For this, the PubMed database was used and no more than 10 years old, randomized clinical studies in humans and that were available were included in full text. A total of 451 items were found, of which the criteria for eligibility, 11 are part of this review. Our study is a literature review which we make a comparison between different authors have used different vitamins, particularly B, C and D during fracture healing and its influence on better or faster effectiveness, comparing between one another vitamin.
[EN] Resently, certain diseases are osteochondral origin such as rheumatoid arthritis or osteoarthritis in certain joints, are of great importance in society. The only vehicle to solve these problems is surgery. There are other strategies to resolve these pathologies that may be of interest, namely the possibility of differentation mesenchymal stem cells to viable chondrocytes serve to repopulate the damaged areas of cartilage in these joints. The purpose of this review was to examine the available scientific evidence to determine the effectiveness of the differentiation of mesenchymal stem cells into chondrocytes in cartilage degenerative diseases. For this, the PubMed database was used and no more than 10 years old, randomized clinical studies in humans and that were available were included in full text. A total of 451 items were found, of which the criteria for eligibility, 11 are part of this review. Our study is a literature review which we make a comparison between different authors have used different vitamins, particularly B, C and D during fracture healing and its influence on better or faster effectiveness, comparing between one another vitamin.